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Posts Tagged ‘clinical trials’

Stay happy to ward off heart disease

Thursday, February 18th, 2010

People who are usually happy and positive tend to have a lower risk of heart disease than those people who aren’t, a study published on 17th February reveals.

Although just an observational study the leading scientist, Dr Karina Davidson, has suggested that it might be possible to help prevent heart disease by enhancing people’s positive emotions.

“We desperately need rigorous clinical trials in this area. If the trials support our findings, then these results will be incredibly important in describing specifically what clinicians and/or patients could do to improve health,”

It is already known that depression and stress significantly increase people’s risk of developing heart disease, but the study is believed to be the first time happiness has been found to lessen the risk of the condition.

Over a period of 10 years, Dr. Davidson and her fellow workers followed 1,739 healthy adults (862 men and 877 women) who were taking part in the 1995 Nova Scotia Health Survey.

After taking account of age, gender, heart risk factors and pessimistic emotions, the study scientists discovered that, over the period of 10-years, increased positive affect predicted less risk of heart-related problem by 22% per point on a five-point scale measuring levels of positive affect expression.

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Dr Davidson said: “Participants with no positive affect were at a 22% higher risk of ischaemic heart disease (heart attack or angina) than those with a little positive affect, who were themselves at 22% higher risk than those with moderate positive affect.

“We also found that if someone, who was usually positive, had some depressive symptoms at the time of the survey, this did not affect their overall lower risk of heart disease.

“As far as we know, this is the first prospective study to examine the relationship between clinically-assessed positive affect and heart disease.”

Read more at Science Daily

Imperial College open a new clinical trials unit

Friday, February 5th, 2010

On 3rd February 2010 a new clinic for setting up and running clinical trials was launched by Imperial College London.

The ICTU will provide a central resource to help scientists apply for funding, design and carry out trials, and analyse their results. It will bring together clinicians, statisticians and trial managers with expertise in every aspect of running clinical trials.

The ICTU was launched by Professor Dame Sally Davies, Director General of Research and Development and Chief Scientific Adviser for the Department of Health and NHS.

The unit will operate as part of Imperial’s Academic Health Science Centre, the unique partnership between Imperial College London and Imperial College Healthcare NHS Trust that formed in October 2007 The AHSC’s aim is to improve the quality of life of patients and populations by taking new discoveries and translating them into new therapies as quickly as possible.

The ICTU incorporates the International Centre for Circulatory Health Trials Unit and the Clinical Trial and Evaluation Unit at the Royal Brompton & Harefield NHS Foundation Trust. It will also work with Imperial’s other partner NHS Trusts.

Are the elderly under-represented in clinical trials?

Tuesday, February 2nd, 2010

An EU funded project has been given the task of finding out if the elderly should be able to take part in more clinical trials. Currently the elderly, who account for high cunsumption, are very often left out of clinical trials. To look at this issue the PREDICT consortium intends to talk to both the stakeholders of older people’s health and the companies who initiate clinical trials.

The consortium started looking at the problem in 2008 and has started to publish its findings:

It is essential to demonstrate the efficacy and safety of drugs. And clinical trials need to take into account issues relevant to this population, i.e. changed metabolism, multiple chronic conditions and polypharmacy. This Charter has been developed as part of PREDICT (www.predicteu.org) a project supported by the EU to investigate in/ exclusion of older people from clinical trials.

Research findings will be presented of systematic reviews of the literature, surveys with health professionals working with older people, and focus groups with patients and carers.

Find out more on the PREDICT website

Welcome to Medtrials

Monday, November 16th, 2009

MedTrials has now a new system that will allow greater, quicker and easier registration for medical trials candidates.  There is also a much simpler search facility for companies to find volunteers to take part in their clinical trials.

Over the coming weeks we will be sending out more information and adding trials to the site.  If you’re interested in taking part, don’t forget to register now and we will make sure that your details get passed to the company undertaking the clinical trial.

News

£73 million centre for translational medicine opens at Imperial

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South West PCTs get £1 million in Research Capability funding

South West PCTs get £1 million in Research Capability funding Go to Source

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Clinilabs expands Phase I presence in New Jersey

Clinilabs expands Phase I presence in New Jersey Go to Source

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Stroke Survivors Benefit From Clot Buster

Results of an international trial show that stroke survivors make a better recovery if they are given the clot-busting drug rt-PA in the first six hours following a stroke… Go to Source

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Combo Of Heat Shock Protein Inhibitor And Hormonal Therapy Being Tested In Breast Cancer Clinical Trial

Pushed to the brink of survival, the hyper-driven cells of a cancerous tumor tap into an ancient system that has helped organisms cope with internal stresses and environmental challenges since life began… Go to Source

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Lung Function Of Patients With Severe Emphysema Improved With Tiny Implanted Coil

A tiny, resilient metal wire designed to gather and compress diseased lung tissue may offer relief to patients with severe heterogeneous emphysema, a subtype of the disease that involves specific, usually isolated areas of the lungs, according to the results of a multicenter international trial conducted in the Netherlands, Germany and France… Go to Source

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